Department of Biological Sciences
State University of New York at Albany, BS in Biology
University of Rochester, M.S. & Ph.D. in Molecular Genetics
University of South Alabama, Post-doctoral fellowship
Office: Biological Sciences Building, Room 241
I attended college at the University of NY at Albany. While working on my BS in Biology I did undergraduate research on yeast in the lab of Dr. Richard Zitomer as well as working summers in the NYS Dept of Health in a sanitary bacteriology laboratory as a chemist’s aide.
With a strong interest in genetics and molecular biology I began the MS/PhD. program in the Dept of Biology at the University of Rochester in the Fall of 1992. I joined the lab of Dr. Animesh Ray with the goal of investigating the SIN1 (Short Integuments 1) gene to determine its role in controlling flowering time in plants. Under Dr. Ray’s guidance I cloned the SIN1 gene, which led to filling and eventually receiving a patent. Besides its obvious role in flowering time, the SIN1 gene (now named DICER-LIKE1) is part of a new class of RNA processing enzymes involved in ‘gene silencing’ now better known as RNA interference. Gene silencing (originally recognized in plants) has since proven to be a breakthrough area of research illustrating a mechanism of RNA-mediated gene regulation of critical importance in many organisms including humans.
After completion of my PhD in 1999, I decided to pursue a completely different research interest and began a post-doctoral fellowship with Dr. Richard Honkanen in the Dept of Biochemistry and Molecular Biology at the Medical School at the University of South Alabama. There, I studied a class of genes called Phosphatases. Phosphatases are enzymes that play an important role in cell signaling cascades by catalyzing the removal of phosphate groups from proteins to either inactivate or activate them.
Current Research interests:
ongoing goal is to examine the roles of Phosphatases in the development of human
cancer and explore their potential use as drug targets for a treatment of
cancer. In the lab now the students and I are specifically studying Protein
Phosphatase 5 (PP5). PP5 expression is increased in breast cancer cells. Current
work suggests that this increase helps make the cancer cells more resistant to
stress resulting from low oxygen conditions (common in tumors). We are studying
the signaling pathways involved in surviving this cell stress.
Animesh Ray and Teresa
Golden, "Gene encoding SHORT INTEGUMENTS1 and uses thereof" Issued May 18, 2004,
US 6,737,561 B1.
Spring 2013 Course Schedule:
Genetics (BIOL 3404) MWF 10:00-10:50 in BS205
Cell and Molecular Biology (BIOL 38141404) MWF 9:00-9:50 in BS201
Bioethics (BIOL 4642) Tues. 5:00-6:50 in BS205
MWF 11-12, Mon. 2-5, Tues. 10-12, Thurs. 9-10, 4-5 and by appointment
Last Modified: January 18, 2013
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